Heryudhanto, Agastya and Ughi, Fuad and Pandjaitan, Maruli (2015) Development and Design of a Measurement Device for Creatinine in Hemodialysis. Bachelor thesis, Swiss German University.

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Abstract

Measurement of Creatinine in the blood is necessary to determine the functionality of kidney where Jaffe method is commonly applied. Several measurement methods have been developed, however concentration of creatinine contained in the blood is insufficient to be detected by conventional sensors alone. In this study, another approach is used to develop measurement method of creatinine in the blood as well as the blood separation technique which consist of blood pre-analysis, and blood analysis. The devices required for analysis of creatinine in blood plasma were constructed and tested for the measurement. Centrifugation and magnetic separation device were constructed and evaluated to obtain optimum separation of the blood. It was noticed that the centrifugation and magnetic separation employed could not optimally separate the blood plasma. Furthermore, spectrophotometer was developed and employed for the blood analysis to obtain the concentration of the creatinine. It is found that the result of the creatine concentration from the developed spectrophotometer shows similar trend compare to the given commercial spectrophotometer. The designed spectrophotometer can perform considerable good accuracy with absolute error of 5.7% which is enough for determination of the end of hemodialysis therapy.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Creatinine; Blood Separation; Spectrophotometer; Hemodialysis; Magnetic Separation.
Subjects:	R Medicine > R Medicine (General) > R856 Biomedical engineering
Divisions:	Faculty of Life Sciences and Technology > Department of Biomedical Engineering
Depositing User:	Atroridho Rizky
Date Deposited:	15 Dec 2020 13:36
Last Modified:	15 Dec 2020 13:36
URI:	http://repository.sgu.ac.id/id/eprint/1581

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