Setyono, Eunike Sawitning Ayu and Ughi, Fuad and Nugroho, Anto Satriyo (2015) Automated Detection of Southeast Asian Ovalocytosis (SAO) Obtained from Thin Blood Smear Microphotographs. Bachelor thesis, Swiss German University.

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Abstract

Southeast Asian Ovalocytosis (SAO) is an erythrocyte disorder, which is characterized by oval-shaped cells with one or two transverse ridges or a longitudinal slit on blood smears. To check the SAO using thin blood smear requires expert manpower and is time consuming. This reach was aimed to automatically detect the SAO from thin blood smear images. Digital images were acquired using a digital camera connected to a light microscope. Images underwent gray-scale conversion to decrease representation of images. Otsu’s Method was implemented to separate blood components and the background. All clumps present in the image were then processed to be separated using recursive bottleneck detection algorithm. The major and minor axes of each extracted erythrocyte were then obtained for the calculation of ratio. The ratio determined whether the erythrocyte is normal or oval, and a count was kept between them. The percentage of oval erythrocyte over total erythrocyte was used as the determination of SAO positive or negative. Thin blood smear sample, prepared and provided by Eijkman Institute for Molecular Biology Indonesia, were used to build and test of the proposed algorithm.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Southeast Asian Ovalocytosis; SAO; Ovalocytosis; Thin Blood Smear; Image Processing; Clump Splitting.
Subjects:	R Medicine > R Medicine (General) > R856 Biomedical engineering R Medicine > RC Internal medicine > RC165 Tropical diseases
Divisions:	Faculty of Life Sciences and Technology > Department of Biomedical Engineering
Depositing User:	Atroridho Rizky
Date Deposited:	15 Dec 2020 13:45
Last Modified:	15 Dec 2020 13:45
URI:	http://repository.sgu.ac.id/id/eprint/1585

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