Detecting and Measuring Concentration of Urea in the Blood Using an Electronic Sensor

Goenawan, Gerald Justin and Pandjaitan, Maruli (2015) Detecting and Measuring Concentration of Urea in the Blood Using an Electronic Sensor. Bachelor thesis, Swiss German University.

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Abstract

People who suffer from chronic kidney disease require the use of hemodialysis. The monitoring of blood urea concentration during therapy is important to evaluate the progress of therapy. The higher the concentration of urea in the blood, the more lethal it is for the patient. Urea is broken down into ammonia and carbon dioxide with the help of enzyme urease. High concentrations of ammonia in the blood can further damage the kidneys. Ammonia ions dissolved in the blood can be detected using a potentiometric conductivity sensor. The sensor has two electrodes that detect changes in electrical potential difference between them. Results show that as the concentration of ammonia dissolved in distilled water increases, the conductivity of the solution increases. On the other hand, an increase in ammonia concentration dissolved in diluted blood would show a decrease in conductivity. This shows that ammonia has an effect on a solution’s overall conductivity, but not as much as the difference caused by blood. The undetected changes made by ammonia in diluted blood can be calculated, and these values can be referred as the fixed relation of ammonia concentration and solution conductivity.

Item Type: Thesis (Bachelor)
Uncontrolled Keywords: Chronic Kidney Disease; Hemodialysis; Potentiometric; Conductivity.
Subjects: Q Science > QA Mathematics > QA75 Electronic computers. Computer science
R Medicine > R Medicine (General) > R856 Biomedical engineering
R Medicine > RB Pathology
Divisions: Faculty of Life Sciences and Technology > Department of Biomedical Engineering
Depositing User: Atroridho Rizky
Date Deposited: 05 Nov 2020 13:51
Last Modified: 05 Nov 2020 13:51
URI: http://repository.sgu.ac.id/id/eprint/1587

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