Fundamentals of Protein-Protein Interactions and Their Methods of Characterization

Audah, Kholis Abdurachim Fundamentals of Protein-Protein Interactions and Their Methods of Characterization. Bioinformatics and Biomedical Research Journal.

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Abstract

Protein-protein interactions are ubiquitous biological phenomena in all types of organism and play vital roles in various metabolic pro-cesses. Therefore, it is very important to understand how protein-protein interactions take place and govern different mechanisms at cellular and molecular levels. Thus, determination of protein-protein interactions is the key in elucidating such mechanisms. In order to provide adequate knowledge and guidance in selecting appropri-ate methods to determine protein-protein interactions, this article will review basic principles, definitions, terminologies, parameters and classification of protein-protein interactions, obtained either from in silico or laboratory experimental works. Some examples of commonly used biochemical and biophysical methods for characteri-zation of protein-protein interactions were also discussed.

Item Type: Article
Subjects: R Medicine > R Medicine (General) > R856 Biomedical engineering
R Medicine > R Medicine (General) > R858 Medical informatics
Divisions: Faculty of Life Sciences and Technology > Department of Biomedical Engineering
Depositing User: Kholis Audah Abdurachim
Date Deposited: 10 Apr 2023 01:39
Last Modified: 14 Apr 2023 06:58
URI: http://repository.sgu.ac.id/id/eprint/2466

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