Audah, Kholis Abdurachim Antibacterial Screening of Mangrove Extract Library: Accelerating Drug Discovery from Indonesian Biodiversity. Antibacterial Screening of Mangrove Extract Library: Accelerating Drug Discovery from Indonesian Biodiversity. (Unpublished)
|
Text (Full text)
Antibacterial Screening of Mangrove Extract Library Accelerating (1).pdf Download (390kB) | Preview |
|
|
Text (Turnitin report)
Biotech-symp-UMS-2019-plagiarism-checked.pdf Download (1MB) | Preview |
Abstract
Humans are at a continuous battle against different types of diseases, so that extraordinary effort to accelerate drug discovery has become a necessity. Indonesian biodiversity is abundant natural resources that can be utilized as potential drug sources. Mangroves are among potential plant medicine that grow nearly at all Indonesian coastlines. The aim of this study was to evaluate the potential of mangrove extracts (extract library) as antibacterial agents. In this study, eight mangroves species were used. There were 16 samples collected from different parts of the plants such as leaf, bark or root. Four types of solvents with different polarity were used producing 64 extracts. Disk diffusion method was used for antibacterial screening using five bacterial strains. There were 37 extracts showed antibacterial potential with the lowest and the highest recorded inhibition index were 0.0283 and 1.8983, respectively. The highest inhibition index was recorded for ethyl acetate extract of root of Bruguiera gymnorrhiza (77 Ea) screened against Escherichia coli. The second highest inhibition index was 0.7867 recorded for leaf of water extract of Avicennia marina (84 A) screened against Staphylococcus aureus. Phytochemical analysis of the extracts were also evaluated. The majority of samples showed saponin and tannin in considerable amount. This supported the data that mangrove extracts were potential as antibacterial agents.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS160 Plant extracts |
| Divisions: | Faculty of Life Sciences and Technology > Department of Biomedical Engineering |
| Depositing User: | Kholis Audah Abdurachim |
| Date Deposited: | 12 Apr 2023 02:45 |
| Last Modified: | 14 Apr 2023 02:13 |
| URI: | http://repository.sgu.ac.id/id/eprint/2534 |
Actions (login required)
 |
View Item |