Audah, Kholis Abdurachim The Effect of Mangrove (Rhizophora Apiculata) Bark Extract Ethanol on Histopathology Pancreas of Male White Rats Sprague Dawley Strain Exposed to Cigarette Smoke. Acta Biochimica Indonesiana.
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Abstract
Background: Cigarette smoke is free radical that causing some pathological conditions such as inflammation, proteolysis, and oxidative stress. In previous studies, mangrove (Rhizophora apiculata) bark extract showed the potential effect as an antioxidant. Mangrove and mangrove associates are abundant plants that grow throughout Indonesian shorelines that have high pharmaceutical and food values. Objective: The purpose of this study is to explore the potential of Rhizophora apiculata bark extract in protecting pancreas of male white rat (Rattus novergicus) Sprague Dawley strain exposed to cigarette smoke. Methods: This research was an experimental study using a posttest-only control group design. Mangrove bark was extracted by using the maceration method. Cigarette smoke exposure was performed using an electric cigarette. Liver inflammation is assessed histopathologically. Results: Significant results (p <0.05) were found between the control and cigarette groups as well as the cigarette and bark extract + control groups. The results were not significant (p> 0.05) between the control and the bark extract + cigarette. Conclusion : The administration of mangrove bark extract has a potential to protect the damage of pancreatic male white rats (Rattus norvegicus) Sprague Dawley strains exposed to cigarette smoke.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) R Medicine > RS Pharmacy and materia medica |
| Divisions: | Faculty of Life Sciences and Technology > Department of Biomedical Engineering |
| Depositing User: | Kholis Audah Abdurachim |
| Date Deposited: | 11 Jan 2024 00:54 |
| Last Modified: | 11 Jan 2024 00:54 |
| URI: | http://repository.sgu.ac.id/id/eprint/2603 |
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The Effect of Mangrove (Rhizophora Apiculata) Bark Extract Ethanol on Histopathology Pancreas of Male White Rats Sprague Dawley Strain Exposed to Cigarette Smoke. (deposited 10 Apr 2023 01:41)
- The Effect of Mangrove (Rhizophora Apiculata) Bark Extract Ethanol on Histopathology Pancreas of Male White Rats Sprague Dawley Strain Exposed to Cigarette Smoke. (deposited 11 Jan 2024 00:54) [Currently Displayed]
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