Kosasih, Jesslyn Nasthasja and Kartawiria, Irvan S. and Maximowitz, Ingolf (2017) Development of Equipment Selection Tool for Pharmaceutical Nanoemulsion Production. Bachelor thesis, Swiss German University.

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Abstract

Nanoemulsions are kinetically stable liquid-in-liquid dispersions with droplet sizes in the range of 20 – 200 nm. Their small size leads to useful properties such as high surface area, robust stability, and optically transparent or translucent appearance. Nanoemulsions are applied in diverse areas such as drug delivery, food, and cosmetics. There are currently four types of mechanical equipment used to prepare nanoemulsions, including high-pressure homogenizer, microfluidizer, ultrasonic homogenizer, and rotor-stator homogenizer. As improper selection of equipment contributes negative effects to the overall performance of manufacturing process i.e. the speed, quality of product, and production cost, the selection of proper equipment becomes an important issue. Based on that reason, an equipment selection tool for nanoemulsions is developed to help manufacturers in selecting the most suitable equipment based on their requirements. The equipment selection tool built in the form of flowchart diagram that consists of four questions relating to the four critical criteria affecting the equipment selection. By following the questions, user could obtain the information of recommended equipment. Moreover, validation was done to ensure the tool could perform its desired function consistently.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Nanoemulsion; High-Pressure Homogenization; Microfluidization; Ultrasonication; Rotor-Stator Homogenization; Equipment Selection Tool
Subjects:	R Medicine > RS Pharmacy and materia medica > RS192 Pharmaceutical technology
Divisions:	Faculty of Life Sciences and Technology > Department of Pharmaceutical Engineering
Depositing User:	Astuti Kusumaningrum
Date Deposited:	19 May 2020 03:32
Last Modified:	20 May 2020 05:13
URI:	http://repository.sgu.ac.id/id/eprint/459

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