Jimmy, Jimmy and Widiputri, Diah Indriani and Gunawan, Paulus (2018) Study Of The Pharmacological Activity And Heavy Metal Content Of Eichhornia Crassipes Extract. Bachelor thesis, Swiss German University.

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Abstract

Eichhornia crassipes is well-known as water hyacinth and it grows rapidly in the nutrient-rich water and high light intensity places. Due to slow capacity of utilising water hyacinth, its growth becomes uncontrollable and has caused many negative impacts to the environment. This work was focused on the study of the total phenolic content, antioxidant activity and anti-microbial activity of water hyacinth in Lake Cipondoh, Tangerang, in order to find the most optimal extraction method for each part of the plant. Fresh water hyacinth was pre-treated through oven-drying and milling process. After that, each part of the plant was macerated by multiple stage extraction method with three different solvents (96% ethanol, water, and 96% ethanol/water) and three variations of sample-to-solvent ratios (1:30, 1:50, and 1:75 w/v). The result of the experiment showed that the leaves of this plant produced an extract with highest TPC (25.35 ± 0.71 mg GAE/g dw) and lowest IC50 (55.76 ± 6.73 ppm) compared to other parts. The most optimum solvent used to achieve this result was 96% ethanol/water (1:1 v/v). In order to obtain highest TPC, the sample to solvent ratio used was 1:75, while 1:50 was used to obtain the lowest IC50. Additionally, in all resulted extracts, flavonoid and saponin was found to be present, while heavy metals content was not detected, which can be assumed to be very low to none. With this result, it was concluded that there is a promising opportunity to apply the water hyacinth growing in Lake Cipondoh, Tangerang as herbal medicine ingredient. Through this utilization, the overall number of water hyacinth in Indonesia can be reduced or at the least be controlled, so that the environmental problem caused by this plant can be minimized.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Water Hyacinth; Phenolic Content; Heavy Metals; Antioxidant Activity; Antimicrobial Activity
Subjects:	R Medicine > RM Therapeutics. Pharmacology > RM262 Anti-infective agents R Medicine > RS Pharmacy and materia medica > RS192 Pharmaceutical technology S Agriculture > SB Plant culture > SB615 Water hyacinth
Divisions:	Faculty of Life Sciences and Technology > Department of Pharmaceutical Engineering
Depositing User:	Astuti Kusumaningrum
Date Deposited:	28 Sep 2020 08:24
Last Modified:	28 Sep 2020 08:24
URI:	http://repository.sgu.ac.id/id/eprint/854

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