Sekarmadidjaja, Melisa Grace and Pandjaitan, Maruli and Marpaung, Abdullah Muzi (2015) Powder Formulation from Butterfly Pea Leaf Extract and its Medical Application for Diabetic Patients. Bachelor thesis, Swiss German University.

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Abstract

Clitoria ternatea L., known as butterfly pea leaves, has been studied for having hypoglycaemic effect on alloxan-induced diabetic mice. With the support from the university through Central Research Fund (CRF) program, the present study was aimed to come up with the freeze-dried butterfly pea leaf powder and to study its effect on diabetic patients. The parameter was concentration of carrier agent, namely maltodextrin, with 3 different levels. The most optimum concentration of maltodextrin was 20% which resulted in 8.67% of moisture content powder with good hygroscopicity. The maltodextrin protected 98.64% of flavonoids and 99.03% of phenols. The freeze-dried butterfly pea leaf extract powder was given to 11 diabetic patients in Dinas Kesehatan Kota Bogor, Bogor, Indonesia, to be consumed twice a day, 1-hour after breakfast and 1-hour after dinner. The results showed no significant different between pre-treatment and post-treatment whole blood haematology, kidney function, and insulin levels. However, all patients with undetected insulin levels had their insulin levels increased. The trend of fasting blood glucose levels of the diabetic patients after consuming butterfly pea leaf extract was negative. 7 out of 11 patients had their fasting blood glucose level decreased, including 3 patients had their blood glucose on the normal range.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Butterfly Pea Leaves; Clitoria Ternatea; Diabetes Mellitus; Hypoglycaemic; Freeze-drying; Blood Glucose; Insulin.
Subjects:	R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS160 Plant extracts T Technology > TP Chemical technology > TP368 Food processing and manufacture
Divisions:	Faculty of Life Sciences and Technology > Department of Food Technology
Depositing User:	Atroridho Rizky
Date Deposited:	28 Dec 2020 16:13
Last Modified:	28 Dec 2020 16:13
URI:	http://repository.sgu.ac.id/id/eprint/1649

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