Characterization and Antioxidant Activity of Gallic Acid Derivative

Sutanto, Hery and Malinda, Krissan (2017) Characterization and Antioxidant Activity of Gallic Acid Derivative. In: International Symposium on Applied Chemistry (ISAC) 2016. AIP Publishing, Melville, New York,, 020030-1-020030-7. ISBN 9780735414716

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Peroxidase enzyme was used to catalyze the dimerization process of gallic acid. The structure of the dimerization product was characterized by 1H NMR and LC-MS-MS. The mechanism of gallic acid dimerization was also discussed. It was proposed that ellagic acid was formed through an oxidative coupling mechanism that lead to the formation of a C-C bond and followed by an intramolecular Fischer esterification mechanism that lead to the formation of two C-O bonds. Moreover, the antioxidant activity of gallic acid and ellagic acid were also studied. Gallic acid and ellagic acid exhibited the DPPH radical scavenging activity with IC50 values of 13.2

Item Type: Book Section
Subjects: H Social Sciences > HD Industries. Land use. Labor > HD9665 Pharmaceutical Industry
Q Science > QK Botany > QK898 Anthocyanins
R Medicine > RS Pharmacy and materia medica > RS192 Pharmaceutical technology
Divisions: Faculty of Life Sciences and Technology > Department of Pharmaceutical Engineering
Depositing User: Faisal Ifzaldi
Date Deposited: 30 Nov 2020 08:58
Last Modified: 30 Nov 2020 08:58

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