Effect of pre-treatment processes and stability testing of lemongrass (Cymbopogon citratus) extract on alpha-glucosidase inhibitor (AGI) and alpha-amylase inhibitor (AAI) activities

Widiputri, Diah Indriani and Mariana, Nadya and Josopandojo, Blandina and Puteri, Maria Dewi P. T. Gunawan and Kartawiria, Irvan S. (2017) Effect of pre-treatment processes and stability testing of lemongrass (Cymbopogon citratus) extract on alpha-glucosidase inhibitor (AGI) and alpha-amylase inhibitor (AAI) activities. In: International Postgraduate Symposium on Food, Agriculture and Biotechnology 2017, August 30 – 31st 2017, Mahasarakham University (MSU) Thailand.

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Abstract

Lemongrass was proved in the previous studies to be one of Indonesian local plants with relatively high activity in inhibiting alpha-glucosidase and alpha-amylase enzymes and thus it can be useful to lower blood glucose level in diabetic patients. This health benefit of lemongrass has unfortunately not been widely explored in the herbal industries. Even though lemongrass has become one of the main raw materials in such industries, the use of lemongrass has been purposed mostly to obtain its aroma and taste. Commercialization of lemongrass as herbal medicine or functional food ingredients with alpha-glucosidase inhibitor (AGI) and alpha-amylase inhibitor (AAI) activities requires a closer study on how these activities can be affected by different pre-treatment processes of fresh lemongrass. In this work, the effect of different washing and drying scenarios during the pre-treatment process of lemongrass extraction on both AGI and AAI activities was studied. The result showed that a combination between 1 time washing and oven drying at 40°C offered the optimum AGI activity. The AAI level was found to be significantly decreased as lemongrass had gone through drying process. However, when compared among different drying methods and different sequences of washing process, the AAI level was found to be relatively unaffected. Stability testing of powdered lemongrass extract was additionally conducted in real time and accelerated conditions to make an estimation of the shelf-life. The shelf-life of powdered lemongrass extract was found to be ± 8 months (at 5°C), ± 3 months (at 25°C) and ± 1.5 months (at 30°C).

Item Type: Conference or Workshop Item (Paper)
Subjects: R Medicine > RS Pharmacy and materia medica > RS160 Plant extracts
T Technology > TP Chemical technology > TP156 Extraction (Chemistry)
Divisions: Faculty of Life Sciences and Technology
Depositing User: Library SGU
Date Deposited: 10 Apr 2023 05:02
Last Modified: 10 Apr 2023 05:02
URI: http://repository.sgu.ac.id/id/eprint/2500

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