Halim, Evelyn Antoinette and Puteri, Maria Dewi P. T. Gunawan and Kato, Eisuke (2019) Analysis of Kelakai (Stenochlaena Palustris) and its Antioxidative, Lipase and Lipid Formation in Adipocytes Inhibitory Capabilities. Bachelor thesis, Swiss German University.

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Abstract

With rising world obesity rates, weight management has become an emerging method to stay healthy. S. palustris which is rich in antioxidants, the lack of which may be related to obesity, was tested to see if it has any potential for managing obesity. Water, 50% methanol and methanol extracts of S. palustris were tested for lipase inhibitory activity and lipid accumulation inhibition in 3T3-L1 adipocytes. DPPH antioxidant activity was also tested. Water extract showed the highest lipase inhibition and methanol extract showed the highest lipid accumulation inhibition in adipocytes. Subsequent fractionation was done on the water extract into first water, 50% methanol and methanol fractions with DIAION HP20 gel. The 50% methanol and methanol fractions were fractionated again into water, 20%, 40%, 60%, 80% and methanol fractions with RP-18 gel. No relationship between antioxidant activity and lipase activity was found as the highest DPPH activity was found in the water fraction of the 50% methanol fraction and the highest lipase inhibitory activity in the methanol fraction of the methanol fraction. LC-MS data corroborate this conclusion.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Obesity ; Antioxidant ; DPPH ; Lipase ; Adipocyte
Subjects:	T Technology > TP Chemical technology > TP368 Food processing and manufacture
Divisions:	Faculty of Life Sciences and Technology > Department of Food Technology
Depositing User:	Adityatama Ratangga
Date Deposited:	18 May 2020 04:53
Last Modified:	18 May 2020 04:53
URI:	http://repository.sgu.ac.id/id/eprint/361

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