Mahadika, Sudono and Rahmawati, Della and Artanti, Nina (2017) Profile of Alpha-Glucosidase Inhibitor from Kalakai (Stenochlaena Palustris) Extract. Bachelor thesis, Swiss German University.

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Abstract

"AGI are components that prevent the occurrence of sugar breakdowns into simple sugar (monosaccharides). AGI commonly consumed as oral medicine to treat diabetes. From the previous studies, several tropical plants in Indonesia have the ability to inhibit α-glucosidase. This study focuses on the potential of Kalakai (Stenochlaena palustris) to be developed into food-safe product. The aim of this study is to select the best extraction method that produce highest yield of AGI activity and later being characterized based on polarities and phenolic content properties. Aqueous (cooked) extract with 12.0 mg/ml concentration from Stenochlaena palustris known to give significant inhibition (approximately 68%) towards α-glucosidase enzyme. Analyzed using Folin-Ciocalteau assay, methanol fraction (19.7 mg/g) and ethyl acetate fraction (12 mg/g) of aqueous extract gave a moderate amount of phenolic contents. However, the AG-inhibition % of both fractions are inferior to AG-inhibition level of the extract itself. While having only a small amount of polyphenols (6.8 mg/g), aqueous extract give a potent AG-inhibition activity. Thus, showing that inorganic materials such as minerals possibly play roles in determining the AG-inhibition level rather than polyphenols inside Stenochlaena palustris, because of the property of water being an inorganic solvent.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Extraction ; Total Phenolic Content ; Stenochlaena Palustris ; Tropical Ferns ; Alpha-Glucosidase Inhibitor
Subjects:	T Technology > TP Chemical technology > TP368 Food processing and manufacture
Divisions:	Faculty of Life Sciences and Technology > Department of Food Technology
Depositing User:	Adityatama Ratangga
Date Deposited:	14 May 2020 05:52
Last Modified:	14 May 2020 05:52
URI:	http://repository.sgu.ac.id/id/eprint/97

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