Lavigne, Yuki and Kartawiria, Irvan S and Maximowitz, Ingolf (2015) Development of Equipment Selection System for Particle Size Reduction. Bachelor thesis, Swiss German University.

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Abstract

Particle size reduction has become an integral part for pharmaceutical development and production. The techniques available for particle size reductions are vary with different mechanism, specification, and requirements. As the technique affects the process efficiency and effectivity, the selection of the right equipment becomes crucial. This study proposed an equipment selection system for recommending equipment for particle size reduction process as well as the priorities index. The equipment selection system built in the form of flowchart that consists of 8 questions relating to the 8 critical parameters of the selection. By following the questions in the equipment selection system, the user could obtain the information of recommended equipment. In addition, a simple computerized equipment selection system was devised to ease the selection process. Furthermore, 3 models; Metformin, Ibuprofen, and Benzoyl peroxide; were used to validate the system by running simulations for those models, which resulted in the recommendation of Disc mill for Metformin with the total priorities index of 1000, Jet mill for Ibuprofen and Benzoyl peroxide with the total priorities index of 480 and 1000.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Particle Size Reduction; Selection System; Comminution; Milling, Diminution.
Subjects:	R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS192 Pharmaceutical technology
Divisions:	Faculty of Life Sciences and Technology > Department of Pharmaceutical Engineering
Depositing User:	Atroridho Rizky
Date Deposited:	18 Dec 2020 16:36
Last Modified:	18 Dec 2020 16:36
URI:	http://repository.sgu.ac.id/id/eprint/1635

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