Darmaya, Paramitta and Pandjaitan, Maruli and Marpaung, Abdullah Muzi (2014) Ready to Drink Soursop Leaves Extract. Bachelor thesis, Swiss German University.
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Abstract
The leaves of the soursop (Annona muricata) contain a bioactive compound called Annonaceous acetogenins. Acetogenins acts as anti-tumor, immunosuppressive, pesticidal, anti-protozoal, anti-helmintic and anti-microbial. The general objective of this research was to produce a ready to drink soursop leaves extract. The extraction of soursop leaves extract was prepared by drying the soursop leaves at 600C. The pulverized dried soursop leaves were then macerated with various temperatures (500, 600, 700, and 800 C) by using ultrasonic bath with the ratio soursop leaves over ethanol 70% 1:10 (g/ml). The extract was concentrated using vacuum rotary evaporator, then the concentrated extract was diluted with water and was mixed with additives and preservatives. Sensory test, proximate analysis and MTT assay analysis was performed to support the research. The results found that soursop leaves extracted at 800C has 78.93% of the NADH inhibition activity was the best extraction temperature among the other temperatures. The most preferred flavor for soursop leaves extract was green tea flavor. The IC50 value was 79.514μg/ml resulted from the MTT analysis in liver cancer cell.
Item Type: | Thesis (Bachelor) |
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Uncontrolled Keywords: | Annona Muricata, Annonaceous Acetogenins, NADH Inhibition Activity, Concentrated Extract, Proximate Analysis, MTT Assay |
Subjects: | T Technology > TP Chemical technology > TP156 Extraction (Chemistry) T Technology > TP Chemical technology > TP368 Food processing and manufacture |
Divisions: | Faculty of Life Sciences and Technology > Department of Food Technology |
Depositing User: | Faisal Ifzaldi |
Date Deposited: | 11 Jul 2021 13:15 |
Last Modified: | 11 Jul 2021 13:15 |
URI: | http://repository.sgu.ac.id/id/eprint/2060 |
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