Santosa, Cosmas Oktavianus and Pandjaitan, Maruli and Marpaung, Abdullah Muzi (2016) Application Of Spray Dried Butterfly Pea Root Extract To Lowering Acethylcholinesterase Levels On Animal Models. Bachelor thesis, Swiss German University.

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Abstract

Butterfly Pea or Clitoria ternatea is a decorative plant found throughout south east asia and india. Though mostly used as a decoration it has been used for a variety of medical symptomps. One of these symptom is Alzheimer’s which is marked with the increase of Acetylcholinesterase enzyme level in the brain and blood. While it is proven that the extract does inhibit the Acetylcholinesterase production only small amounts of the extract can be made at a time. A new method of extraction using a spray dryer is used to create larger amounts of the Extract but with lower concentrations compared to the traditional technique of freeze drying extraction. To learn if the Lower concentration can still effectively treat Alzheimer’s this experiment was done. The Alzheimer’s disease in this experiment are induced using high amounts of scopolamine. While there were significant difference before and after the treatment the decrease of the acetylcholinesterase levels are insignificant between the groups. The results prompted a scientific guess whereas the decrease of acetylcholinesterase levels in the rats are naturally occurring phenomenon. At the same time the data shows potential that the treatment and the dosage maybe the key to getting better results.

Item Type:	Thesis (Bachelor)
Uncontrolled Keywords:	Butterfly Pea Root; Clitoria Ternatea; Alzheimer’s Disease; Acetylcholinesterase Enzyme; Root Extraction
Subjects:	R Medicine > RS Pharmacy and materia medica > RS160 Plant extracts T Technology > TP Chemical technology > TP368 Food processing and manufacture
Divisions:	Faculty of Life Sciences and Technology > Department of Food Technology
Depositing User:	Astuti Kusumaningrum
Date Deposited:	25 Sep 2020 08:39
Last Modified:	25 Sep 2020 08:39
URI:	http://repository.sgu.ac.id/id/eprint/886

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